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Bid-Induced Release of AIF/EndoG from Mitochondria Causes Apoptosis of Macrophages during Infection with Leptospira interrogans

Leptospirosis is a global zoonotic infectious disease caused by pathogenic Leptospira species. Leptospire-induced macrophage apoptosis through the Fas/FasL-caspase-8/3 pathway plays an important role in the survival and proliferation of the pathogen in hosts. Although, the release of mitochondrial a...

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Detalles Bibliográficos
Autores principales: Hu, Wei-Lin, Dong, Hai-Yan, Li, Yang, Ojcius, David M., Li, Shi-Jun, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694448/
https://www.ncbi.nlm.nih.gov/pubmed/29184851
http://dx.doi.org/10.3389/fcimb.2017.00471