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Bid-Induced Release of AIF/EndoG from Mitochondria Causes Apoptosis of Macrophages during Infection with Leptospira interrogans
Leptospirosis is a global zoonotic infectious disease caused by pathogenic Leptospira species. Leptospire-induced macrophage apoptosis through the Fas/FasL-caspase-8/3 pathway plays an important role in the survival and proliferation of the pathogen in hosts. Although, the release of mitochondrial a...
Autores principales: | Hu, Wei-Lin, Dong, Hai-Yan, Li, Yang, Ojcius, David M., Li, Shi-Jun, Yan, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694448/ https://www.ncbi.nlm.nih.gov/pubmed/29184851 http://dx.doi.org/10.3389/fcimb.2017.00471 |
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