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Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

We recently reported that increased levels of Adiponectin (ApN) in the brain led to microglia phenotype and activation state regulation, thus reducing both global brain inflammation and depressive-like behaviors in mice. Apart from this, little is known on ApN molecular effects on microglia, althoug...

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Detalles Bibliográficos
Autores principales: Nicolas, Sarah, Cazareth, Julie, Zarif, Hadi, Guyon, Alice, Heurteaux, Catherine, Chabry, Joëlle, Petit-Paitel, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694456/
https://www.ncbi.nlm.nih.gov/pubmed/29184485
http://dx.doi.org/10.3389/fncel.2017.00352