Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H(3) and H(4) Receptors with Anti-inflammatory Potential

The histamine receptors (HRs) are traditional G protein-coupled receptors of extensive therapeutic interest. Recently, H(3)R and H(4)R subtypes have been targeted in drug discovery projects for inflammation, asthma, pain, cancer, Parkinson’s, and Alzheimer’s diseases, which includes searches for dua...

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Detalles Bibliográficos
Autores principales: Corrêa, Michelle F., Barbosa, Álefe J. R., Teixeira, Larissa B., Duarte, Diego A., Simões, Sarah C., Parreiras-e-Silva, Lucas T., Balbino, Aleksandro M., Landgraf, Richardt G., Bouvier, Michel, Costa-Neto, Claudio M., Fernandes, João P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694482/
https://www.ncbi.nlm.nih.gov/pubmed/29184503
http://dx.doi.org/10.3389/fphar.2017.00825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694482/
https://www.ncbi.nlm.nih.gov/pubmed/29184503
http://dx.doi.org/10.3389/fphar.2017.00825

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