Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage

Accumulation of advanced glycation end products (AGEs) contributes to ageing and age-related diseases, especially type 2 diabetes. The NLRP3 inflammasome, as a vital component of the innate immune system, is implicated in the pathogenesis of type 2 diabetes. However, the role of the NLRP3 inflammaso...

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Detalles Bibliográficos
Autores principales: Kong, Xiang, Lu, Ai-Ling, Yao, Xin-Ming, Hua, Qiang, Li, Xiao-Yong, Qin, Li, Zhang, Hong-Mei, Meng, Guang-Xun, Su, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694574/
https://www.ncbi.nlm.nih.gov/pubmed/29230270
http://dx.doi.org/10.1155/2017/9692546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694574/
https://www.ncbi.nlm.nih.gov/pubmed/29230270
http://dx.doi.org/10.1155/2017/9692546

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