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Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage

Accumulation of advanced glycation end products (AGEs) contributes to ageing and age-related diseases, especially type 2 diabetes. The NLRP3 inflammasome, as a vital component of the innate immune system, is implicated in the pathogenesis of type 2 diabetes. However, the role of the NLRP3 inflammaso...

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Detalles Bibliográficos
Autores principales:	Kong, Xiang, Lu, Ai-Ling, Yao, Xin-Ming, Hua, Qiang, Li, Xiao-Yong, Qin, Li, Zhang, Hong-Mei, Meng, Guang-Xun, Su, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694574/ https://www.ncbi.nlm.nih.gov/pubmed/29230270 http://dx.doi.org/10.1155/2017/9692546

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