Measuring quantitative effects of methylation on transcription factor–DNA binding affinity

Methylation of CpG (cytosine-phosphate-guanine) dinucleotides is a common epigenetic mark that influences gene expression. The effects of methylation on transcription factor (TF) binding are unknown for most TFs and, even when known, such knowledge is often only qualitative. In reality, methylation...

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Detalles Bibliográficos
Autores principales: Zuo, Zheng, Roy, Basab, Chang, Yiming Kenny, Granas, David, Stormo, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694663/
https://www.ncbi.nlm.nih.gov/pubmed/29159284
http://dx.doi.org/10.1126/sciadv.aao1799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694663/
https://www.ncbi.nlm.nih.gov/pubmed/29159284
http://dx.doi.org/10.1126/sciadv.aao1799

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