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Orexin modulates behavioral fear expression through the locus coeruleus

Emotionally salient information activates orexin neurons in the lateral hypothalamus, leading to increase in sympathetic outflow and vigilance level. How this circuit alters animals’ behavior remains unknown. Here we report that noradrenergic neurons in the locus coeruleus (NA(LC) neurons) projectin...

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Detalles Bibliográficos
Autores principales: Soya, Shingo, Takahashi, Tohru M., McHugh, Thomas J., Maejima, Takashi, Herlitze, Stefan, Abe, Manabu, Sakimura, Kenji, Sakurai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694764/
https://www.ncbi.nlm.nih.gov/pubmed/29151577
http://dx.doi.org/10.1038/s41467-017-01782-z