Cargando…
Orexin modulates behavioral fear expression through the locus coeruleus
Emotionally salient information activates orexin neurons in the lateral hypothalamus, leading to increase in sympathetic outflow and vigilance level. How this circuit alters animals’ behavior remains unknown. Here we report that noradrenergic neurons in the locus coeruleus (NA(LC) neurons) projectin...
Autores principales: | Soya, Shingo, Takahashi, Tohru M., McHugh, Thomas J., Maejima, Takashi, Herlitze, Stefan, Abe, Manabu, Sakimura, Kenji, Sakurai, Takeshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694764/ https://www.ncbi.nlm.nih.gov/pubmed/29151577 http://dx.doi.org/10.1038/s41467-017-01782-z |
Ejemplares similares
-
Chronic Alterations in Monoaminergic Cells in the Locus Coeruleus in Orexin Neuron-Ablated Narcoleptic Mice
por: Tsujino, Natsuko, et al.
Publicado: (2013) -
Evolution of Orexin Neuropeptide System: Structure and Function
por: Soya, Shingo, et al.
Publicado: (2020) -
Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture
por: Saito, Yuki C., et al.
Publicado: (2018) -
GABAergic neurons in the preoptic area send direct inhibitory projections to orexin neurons
por: Saito, Yuki C., et al.
Publicado: (2013) -
Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice
por: Chowdhury, Srikanta, et al.
Publicado: (2019)