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Rhynchophylline Ameliorates Endothelial Dysfunction via Src-PI3K/Akt-eNOS Cascade in the Cultured Intrarenal Arteries of Spontaneous Hypertensive Rats

Objectives: To examine the protective effect of Rhynchophylline (Rhy) on vascular endothelial function in spontaneous hypertensive rats (SHRs) and the underlying mechanism. Methods: Intrarenal arteries of SHRs and Wistar rats were suspended in myograph for force measurement. Expression and phosphory...

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Detalles Bibliográficos
Autores principales: Hao, Hui-Feng, Liu, Li-Mei, Pan, Chun-Shui, Wang, Chuan-She, Gao, Yuan-Sheng, Fan, Jing-Yu, Han, Jing-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694770/
https://www.ncbi.nlm.nih.gov/pubmed/29187825
http://dx.doi.org/10.3389/fphys.2017.00928