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Adrenomedullin Contributes to Age-Related Memory Loss in Mice and Is Elevated in Aging Human Brains

Memory decline is common in elderly individuals and is the hallmark of Alzheimer’s disease (AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and hippocampus, caused in part by cytoskeleton disruption. Adrenomedullin (AM) and its gene-related peptide, proadrenomedullin...

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Detalles Bibliográficos
Autores principales: Larrayoz, Ignacio M., Ferrero, Hilda, Martisova, Eva, Gil-Bea, Francisco J., Ramírez, María J., Martínez, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694777/
https://www.ncbi.nlm.nih.gov/pubmed/29187812
http://dx.doi.org/10.3389/fnmol.2017.00384