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Adrenomedullin Contributes to Age-Related Memory Loss in Mice and Is Elevated in Aging Human Brains
Memory decline is common in elderly individuals and is the hallmark of Alzheimer’s disease (AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and hippocampus, caused in part by cytoskeleton disruption. Adrenomedullin (AM) and its gene-related peptide, proadrenomedullin...
Autores principales: | Larrayoz, Ignacio M., Ferrero, Hilda, Martisova, Eva, Gil-Bea, Francisco J., Ramírez, María J., Martínez, Alfredo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694777/ https://www.ncbi.nlm.nih.gov/pubmed/29187812 http://dx.doi.org/10.3389/fnmol.2017.00384 |
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