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Functional assessment of human enhancer activities using whole-genome STARR-sequencing

BACKGROUND: Genome-wide quantification of enhancer activity in the human genome has proven to be a challenging problem. Recent efforts have led to the development of powerful tools for enhancer quantification. However, because of genome size and complexity, these tools have yet to be applied to the...

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Detalles Bibliográficos
Autores principales: Liu, Yuwen, Yu, Shan, Dhiman, Vineet K., Brunetti, Tonya, Eckart, Heather, White, Kevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694901/
https://www.ncbi.nlm.nih.gov/pubmed/29151363
http://dx.doi.org/10.1186/s13059-017-1345-5