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A coarse-grained computational model of the nuclear pore complex predicts Phe-Gly nucleoporin dynamics

The phenylalanine-glycine–repeat nucleoporins (FG-Nups), which occupy the lumen of the nuclear pore complex (NPC), are critical for transport between the nucleus and cytosol. Although NPCs differ in composition across species, they are largely conserved in organization and function. Transport throug...

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Detalles Bibliográficos
Autores principales: Pulupa, Joan, Rachh, Manas, Tomasini, Michael D., Mincer, Joshua S., Simon, Sanford M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694938/
https://www.ncbi.nlm.nih.gov/pubmed/28887410
http://dx.doi.org/10.1085/jgp.201711769