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ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis

The intestinal epithelium continually self‐renews and can rapidly regenerate after damage. Dysregulation of intestinal epithelial homeostasis leads to severe inflammatory bowel disease. Additionally, aberrant signaling by the secreted protein angiopoietin‐like protein 2 (ANGPTL2) causes chronic infl...

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Detalles Bibliográficos
Autores principales: Horiguchi, Haruki, Endo, Motoyoshi, Kawane, Kohki, Kadomatsu, Tsuyoshi, Terada, Kazutoyo, Morinaga, Jun, Araki, Kimi, Miyata, Keishi, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694950/
https://www.ncbi.nlm.nih.gov/pubmed/28043948
http://dx.doi.org/10.15252/embj.201695690