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ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis
The intestinal epithelium continually self‐renews and can rapidly regenerate after damage. Dysregulation of intestinal epithelial homeostasis leads to severe inflammatory bowel disease. Additionally, aberrant signaling by the secreted protein angiopoietin‐like protein 2 (ANGPTL2) causes chronic infl...
Autores principales: | Horiguchi, Haruki, Endo, Motoyoshi, Kawane, Kohki, Kadomatsu, Tsuyoshi, Terada, Kazutoyo, Morinaga, Jun, Araki, Kimi, Miyata, Keishi, Oike, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694950/ https://www.ncbi.nlm.nih.gov/pubmed/28043948 http://dx.doi.org/10.15252/embj.201695690 |
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