pH-Sensitive Nano-Complexes Overcome Drug Resistance and Inhibit Metastasis of Breast Cancer by Silencing Akt Expression

The therapy of breast cancer is encumbered by drug resistance and metastasis, which can be due to a defective PI3K/AKT/mTOR signaling pathway. This study was aimed at improving the anti-cancer effect of the chemotherapeutic agent paclitaxel (PTX) on the drug resistant and metastatic breast cancer by...

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Detalles Bibliográficos
Autores principales: Yin, Jieying, Lang, Tianqun, Cun, Dongmei, Zheng, Zhong, Huang, Yan, Yin, Qi, Yu, Haijun, Li, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695007/
https://www.ncbi.nlm.nih.gov/pubmed/29158820
http://dx.doi.org/10.7150/thno.21516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695007/
https://www.ncbi.nlm.nih.gov/pubmed/29158820
http://dx.doi.org/10.7150/thno.21516

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