Local and Systemic CD4(+) T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis

Investigation of the Th1 immune response in sarcoidosis CD4(+) T cells has revealed reduced proliferative capacity and cytokine expression upon TCR stimulation. In other disease models, such cellular dysfunction has been associated with a step-wise, progressive loss of T cell function that results f...

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Detalles Bibliográficos
Autores principales: Hawkins, Charlene, Shaginurova, Guzel, Shelton, D. Auriel, Herazo-Maya, Jose D., Oswald-Richter, Kyra A., Rotsinger, Joseph E., Young, Anjuli, Celada, Lindsay J., Kaminski, Naftali, Sevin, Carla, Drake, Wonder P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695030/
https://www.ncbi.nlm.nih.gov/pubmed/29234685
http://dx.doi.org/10.1155/2017/3642832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695030/
https://www.ncbi.nlm.nih.gov/pubmed/29234685
http://dx.doi.org/10.1155/2017/3642832

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