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Local and Systemic CD4(+) T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis
Investigation of the Th1 immune response in sarcoidosis CD4(+) T cells has revealed reduced proliferative capacity and cytokine expression upon TCR stimulation. In other disease models, such cellular dysfunction has been associated with a step-wise, progressive loss of T cell function that results f...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695030/ https://www.ncbi.nlm.nih.gov/pubmed/29234685 http://dx.doi.org/10.1155/2017/3642832 |