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Ets2 anchors the prometastatic function of mutant p53 in osteosarcoma

Mutations in the tumor suppressor p53 occur in a majority of human cancers. Some gain-of-function (GOF) p53 mutations endow tumor cells with increased metastatic ability, although our understanding of the underlying mechanism remains incomplete. In this issue of Genes & Development, Pourebrahim...

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Detalles Bibliográficos
Autores principales: Liu, Daniel D., Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695082/
https://www.ncbi.nlm.nih.gov/pubmed/29051386
http://dx.doi.org/10.1101/gad.307439.117