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Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation

Quaking protein isoforms arise from a single Quaking gene and bind the same RNA motif to regulate splicing, translation, decay, and localization of a large set of RNAs. However, the mechanisms by which Quaking expression is controlled to ensure that appropriate amounts of each isoform are available...

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Detalles Bibliográficos
Autores principales: Fagg, W. Samuel, Liu, Naiyou, Fair, Jeffrey Haskell, Shiue, Lily, Katzman, Sol, Donohue, John Paul, Ares, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695090/
https://www.ncbi.nlm.nih.gov/pubmed/29021242
http://dx.doi.org/10.1101/gad.302059.117