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Clinical Translation and First In-Human Use of [(44)Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer

Background: Various trivalent radiometals are well suited for labeling of DOTA-conjugated variants of Glu-ureido-based prostate-specific membrane antigen (PSMA) inhibitors. The DOTA-conjugate PSMA-617 has proven high potential in PSMA radioligand therapy (PSMA-RLT) of prostate cancer as well as PET...

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Detalles Bibliográficos
Autores principales: Eppard, Elisabeth, de la Fuente, Ana, Benešová, Martina, Khawar, Ambreen, Bundschuh, Ralph A., Gärtner, Florian C., Kreppel, Barbara, Kopka, Klaus, Essler, Markus, Rösch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695136/
https://www.ncbi.nlm.nih.gov/pubmed/29158832
http://dx.doi.org/10.7150/thno.20586