MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain

Rationale: Signal transducer and activator of transcription-3 (STAT3) plays a pivotal role in cancer biology. Many small-molecule inhibitors that target STAT3 have been developed as potential anticancer drugs. While designing small-molecule inhibitors that target the SH2 domain of STAT3 remains the...

Descripción completa

Detalles Bibliográficos
Autores principales: Son, Dong Ju, Zheng, Jie, Jung, Yu Yeon, Hwang, Chul Ju, Lee, Hee Pom, Woo, Ju Rang, Baek, Song Yi, Ham, Young Wan, Kang, Min Woong, Shong, Minho, Kweon, Gi Ryang, Song, Min Jong, Jung, Jae Kyung, Han, Sang-Bae, Kim, Bo Yeon, Yoon, Do Young, Choi, Bu Young, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695154/
https://www.ncbi.nlm.nih.gov/pubmed/29158850
http://dx.doi.org/10.7150/thno.18630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695154/
https://www.ncbi.nlm.nih.gov/pubmed/29158850
http://dx.doi.org/10.7150/thno.18630

Ejemplares similares