In silico-based identification of human α-enolase inhibitors to block cancer cell growth metabolically

Unlimited growth of cancer cells requires an extensive nutrient supply. To meet this demand, cancer cells drastically upregulate glucose uptake and metabolism compared to normal cells. This difference has made the blocking of glycolysis a fascinating strategy to treat this malignant disease. α-enola...

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Detalles Bibliográficos
Autores principales: Lung, Jrhau, Chen, Kuan-Liang, Hung, Chien-Hui, Chen, Chih-Cheng, Hung, Ming-Szu, Lin, Yu-Ching, Wu, Ching-Yuan, Lee, Kuan-Der, Shih, Neng-Yao, Tsai, Ying Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695255/
https://www.ncbi.nlm.nih.gov/pubmed/29180852
http://dx.doi.org/10.2147/DDDT.S149214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695255/
https://www.ncbi.nlm.nih.gov/pubmed/29180852
http://dx.doi.org/10.2147/DDDT.S149214

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