Differences of statin activity in 2D and 3D pancreatic cancer cell cultures

PURPOSE: To evaluate the anticancer activity of lovastatin (LOVA), mevastatin (MEVA), pitavastatin (PITA), and simvastatin (SIMVA) in 2D and 3D models of three human pancreatic cancer cell lines (BxPC-3, MIA PaCa-2, and PANC-1). METHODS: The effect of statins on cell viability was estimated by 3-(4,...

Descripción completa

Detalles Bibliográficos
Autores principales: Paškevičiūtė, Miglė, Petrikaitė, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695256/
https://www.ncbi.nlm.nih.gov/pubmed/29180851
http://dx.doi.org/10.2147/DDDT.S149411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695256/
https://www.ncbi.nlm.nih.gov/pubmed/29180851
http://dx.doi.org/10.2147/DDDT.S149411

Ejemplares similares