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Differences of statin activity in 2D and 3D pancreatic cancer cell cultures

PURPOSE: To evaluate the anticancer activity of lovastatin (LOVA), mevastatin (MEVA), pitavastatin (PITA), and simvastatin (SIMVA) in 2D and 3D models of three human pancreatic cancer cell lines (BxPC-3, MIA PaCa-2, and PANC-1). METHODS: The effect of statins on cell viability was estimated by 3-(4,...

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Detalles Bibliográficos
Autores principales:	Paškevičiūtė, Miglė, Petrikaitė, Vilma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695256/ https://www.ncbi.nlm.nih.gov/pubmed/29180851 http://dx.doi.org/10.2147/DDDT.S149411

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