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Whole-genome DNA methylation characteristics in pediatric precursor B cell acute lymphoblastic leukemia (BCP ALL)

In addition to genetic alterations, epigenetic abnormalities have been shown to underlie the pathogenesis of acute lymphoblastic leukemia (ALL)—the most common pediatric cancer. The purpose of this study was to characterize the whole genome DNA methylation profile in children with precursor B-cell A...

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Detalles Bibliográficos
Autores principales: Chaber, Radosław, Gurgul, Artur, Wróbel, Grażyna, Haus, Olga, Tomoń, Anna, Kowalczyk, Jerzy, Szmatoła, Tomasz, Jasielczuk, Igor, Rybka, Blanka, Ryczan-Krawczyk, Renata, Duszeńko, Ewa, Stąpor, Sylwia, Ciebiera, Krzysztof, Paszek, Sylwia, Potocka, Natalia, Arthur, Christopher J., Zawlik, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695275/
https://www.ncbi.nlm.nih.gov/pubmed/29125853
http://dx.doi.org/10.1371/journal.pone.0187422