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Insulin resistance enhances the mitogen-activated protein kinase signaling pathway in ovarian granulosa cells

The ovary is the main regulator of female fertility. Granulosa cell dysfunction may be involved in various reproductive endocrine disorders. Here we investigated the effect of insulin resistance on the metabolism and function of ovarian granulosa cells, and dissected the functional status of the mit...

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Detalles Bibliográficos
Autores principales: Kong, Linghui, Wang, Qien, Jin, Jiewen, Xiang, Zou, Chen, Taoyu, Shen, Shanmei, Wang, Hongwei, Gao, Qian, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695281/
https://www.ncbi.nlm.nih.gov/pubmed/29125859
http://dx.doi.org/10.1371/journal.pone.0188029