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Insulin resistance enhances the mitogen-activated protein kinase signaling pathway in ovarian granulosa cells
The ovary is the main regulator of female fertility. Granulosa cell dysfunction may be involved in various reproductive endocrine disorders. Here we investigated the effect of insulin resistance on the metabolism and function of ovarian granulosa cells, and dissected the functional status of the mit...
Autores principales: | Kong, Linghui, Wang, Qien, Jin, Jiewen, Xiang, Zou, Chen, Taoyu, Shen, Shanmei, Wang, Hongwei, Gao, Qian, Wang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695281/ https://www.ncbi.nlm.nih.gov/pubmed/29125859 http://dx.doi.org/10.1371/journal.pone.0188029 |
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