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What Happens After Menopause? (WHAM): protocol for a prospective, multicentre, age-matched cohort trial of risk-reducing bilateral salpingo-oophorectomy in high-risk premenopausal women

INTRODUCTION: Women at high inherited risk of ovarian cancer are advised to undergo risk-reducing bilateral salpingo-oophorectomy (RRBSO) at age 40–45 years or when their families are complete. Most women are premenopausal at this age, so RRBSO will induce surgical menopause. Despite the clear benef...

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Detalles Bibliográficos
Autores principales: Hickey, Martha, Trainer, Alison, Braat, Sabine, Davey, Mary-Ann, Krejany, Efrosinia, Wark, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695307/
https://www.ncbi.nlm.nih.gov/pubmed/29138210
http://dx.doi.org/10.1136/bmjopen-2017-018758