Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism

BACKGROUND: Family studies have shown a strong heritability component for venous thromboembolism (VTE), but established genetic risk factors are present in only half of VTE patients. AIM: To identify genetic risk factors in two large families with unexplained hereditary VTE. METHODS: We performed wh...

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Detalles Bibliográficos
Autores principales: Cunha, Marisa L. R., Meijers, Joost C. M., Rosendaal, Frits R., Vlieg, Astrid van Hylckama, Reitsma, Pieter H., Middeldorp, Saskia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695603/
https://www.ncbi.nlm.nih.gov/pubmed/29117201
http://dx.doi.org/10.1371/journal.pone.0187699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695603/
https://www.ncbi.nlm.nih.gov/pubmed/29117201
http://dx.doi.org/10.1371/journal.pone.0187699

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