Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization

There is growing interest in studying and engineering integral membrane proteins (MPs) that play key roles in sensing and regulating cellular response to diverse external signals. A MP must be expressed, correctly inserted and folded in a lipid bilayer, and trafficked to the proper cellular location...

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Detalles Bibliográficos
Autores principales: Bedbrook, Claire N., Yang, Kevin K., Rice, Austin J., Gradinaru, Viviana, Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695628/
https://www.ncbi.nlm.nih.gov/pubmed/29059183
http://dx.doi.org/10.1371/journal.pcbi.1005786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695628/
https://www.ncbi.nlm.nih.gov/pubmed/29059183
http://dx.doi.org/10.1371/journal.pcbi.1005786

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