Cargando…
Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization
There is growing interest in studying and engineering integral membrane proteins (MPs) that play key roles in sensing and regulating cellular response to diverse external signals. A MP must be expressed, correctly inserted and folded in a lipid bilayer, and trafficked to the proper cellular location...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695628/ https://www.ncbi.nlm.nih.gov/pubmed/29059183 http://dx.doi.org/10.1371/journal.pcbi.1005786 |