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Automated deconvolution of structured mixtures from heterogeneous tumor genomic data

With increasing appreciation for the extent and importance of intratumor heterogeneity, much attention in cancer research has focused on profiling heterogeneity on a single patient level. Although true single-cell genomic technologies are rapidly improving, they remain too noisy and costly at presen...

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Detalles Bibliográficos
Autores principales: Roman, Theodore, Xie, Lu, Schwartz, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695636/
https://www.ncbi.nlm.nih.gov/pubmed/29059177
http://dx.doi.org/10.1371/journal.pcbi.1005815