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Automated deconvolution of structured mixtures from heterogeneous tumor genomic data
With increasing appreciation for the extent and importance of intratumor heterogeneity, much attention in cancer research has focused on profiling heterogeneity on a single patient level. Although true single-cell genomic technologies are rapidly improving, they remain too noisy and costly at presen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695636/ https://www.ncbi.nlm.nih.gov/pubmed/29059177 http://dx.doi.org/10.1371/journal.pcbi.1005815 |