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The Structural Role of Elastic Fibers in the Cornea Investigated Using a Mouse Model for Marfan Syndrome

PURPOSE: The presence of fibrillin-rich elastic fibers in the cornea has been overlooked in recent years. The aim of the current study was to elucidate their functional role using a mouse model for Marfan syndrome, defective in fibrillin-1, the major structural component of the microfibril bundles t...

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Detalles Bibliográficos
Autores principales: White, Tomas L., Lewis, Philip, Hayes, Sally, Fergusson, James, Bell, James, Farinha, Luis, White, Nick S., Pereira, Lygia V., Meek, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695733/
https://www.ncbi.nlm.nih.gov/pubmed/28395026
http://dx.doi.org/10.1167/iovs.16-21358