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Tocilizumab potentially prevents bone loss in patients with anticitrullinated protein antibody-positive rheumatoid arthritis

Rheumatoid arthritis (RA) is associated with a high risk of osteoporosis and fracture. Interleukin (IL)-6 inhibitors may suppress osteoclast activation. Anticitrullinated protein antibody (ACPA) titers are inversely associated with bone mineral density (BMD). However, the differential effect of ACPA...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ming, Chen, Hsin-Hua, Huang, Wen-Nan, Liao, Tsai-Ling, Chen, Jun-Peng, Chao, Wen-Cheng, Lin, Ching-Tsai, Hung, Wei-Ting, Hsieh, Chia-Wei, Hsieh, Tsu-Yi, Chen, Yi-Hsing, Chen, Der-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695761/
https://www.ncbi.nlm.nih.gov/pubmed/29155868
http://dx.doi.org/10.1371/journal.pone.0188454