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Impaired AQP2 trafficking in Fxyd1 knockout mice: A role for FXYD1 in regulated vesicular transport

The final adjustment of urine volume occurs in the inner medullary collecting duct (IMCD), chiefly mediated by the water channel aquaporin 2 (AQP2). With vasopressin stimulation, AQP2 accumulation in the apical plasma membrane of principal cells allows water reabsorption from the lumen. We report th...

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Detalles Bibliográficos
Autores principales: Arystarkhova, Elena, Bouley, Richard, Liu, Yi Bessie, Sweadner, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695786/
https://www.ncbi.nlm.nih.gov/pubmed/29155857
http://dx.doi.org/10.1371/journal.pone.0188006