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The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice

In search of the sequence of pathogenic events leading to glucocorticoid-induced osteonecrosis, we determined the molecular, biomechanical, cellular, and vascular changes in the femur of C57BL/6 mice receiving prednisolone for 14, 28, or 42 days. The femoral head, but not the distal femur, of mice t...

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Detalles Bibliográficos
Autores principales: Weinstein, Robert S., Hogan, Erin A., Borrelli, Michael J., Liachenko, Serguei, O’Brien, Charles A., Manolagas, Stavros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695837/
https://www.ncbi.nlm.nih.gov/pubmed/28938402
http://dx.doi.org/10.1210/en.2017-00662