Capacity of tTreg generation is not impaired in the atrophied thymus

Postnatal thymic epithelial cell (TEC) homeostatic defect- or natural aging-induced thymic atrophy results in a decline in central T-cell tolerance establishment, which is constituted by thymocyte negative selection and cluster of differentiation (CD) 4(+) thymic regulatory T (tTreg) cell generation...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Jiyoung, Wang, Weikan, Thomas, Rachel, Su, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695848/
https://www.ncbi.nlm.nih.gov/pubmed/29117183
http://dx.doi.org/10.1371/journal.pbio.2003352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695848/
https://www.ncbi.nlm.nih.gov/pubmed/29117183
http://dx.doi.org/10.1371/journal.pbio.2003352

Ejemplares similares