PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly

The tumor suppressor PTEN executes cellular functions predominantly through its phosphatase activity. Here we identified a phosphatase-independent role for PTEN during vesicular trafficking of the glucose transporter GLUT1. PTEN physically interacts with SNX27, a component of the retromer complex th...

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Detalles Bibliográficos
Autores principales: Shinde, Swapnil Rohidas, Maddika, Subbareddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695913/
https://www.ncbi.nlm.nih.gov/pubmed/29117568
http://dx.doi.org/10.1016/j.celrep.2017.10.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695913/
https://www.ncbi.nlm.nih.gov/pubmed/29117568
http://dx.doi.org/10.1016/j.celrep.2017.10.053

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