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Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs

Ronin (THAP11), a DNA-binding protein that evolved from a primordial DNA transposon by molecular domestication, recognizes a hyperconserved promoter sequence to control developmentally and metabolically essential genes in pluripotent stem cells. However, it remains unclear whether Ronin or related T...

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Detalles Bibliográficos
Autores principales: Fujita, Jun, Freire, Pablo, Coarfa, Cristian, Benham, Ashley L., Gunaratne, Preethi, Schneider, Michael D., Dejosez, Marion, Zwaka, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695914/
https://www.ncbi.nlm.nih.gov/pubmed/29117561
http://dx.doi.org/10.1016/j.celrep.2017.10.036