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Primer-Independent DNA Synthesis by a Family B DNA Polymerase from Self-Replicating Mobile Genetic Elements

Family B DNA polymerases (PolBs) play a central role during replication of viral and cellular chromosomes. Here, we report the discovery of a third major group of PolBs, which we denote primer-independent PolB (piPolB), that might be a link between the previously known protein-primed and RNA/DNA-pri...

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Detalles Bibliográficos
Autores principales: Redrejo-Rodríguez, Modesto, Ordóñez, Carlos D., Berjón-Otero, Mónica, Moreno-González, Juan, Aparicio-Maldonado, Cristian, Forterre, Patrick, Salas, Margarita, Krupovic, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695915/
https://www.ncbi.nlm.nih.gov/pubmed/29117562
http://dx.doi.org/10.1016/j.celrep.2017.10.039