Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism

Fibroblast Growth Factor Receptor (FGFR) signaling is a complex pathway which controls several processes, including cell proliferation, survival, migration, and metabolism. FGFR1 signaling is frequently deregulated via amplification/over-expression in NSCLC of squamous histotype (SQCLC), however its...

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Detalles Bibliográficos
Autores principales: Fumarola, Claudia, Cretella, Daniele, La Monica, Silvia, Bonelli, Mara A., Alfieri, Roberta, Caffarra, Cristina, Quaini, Federico, Madeddu, Denise, Falco, Angela, Cavazzoni, Andrea, Digiacomo, Graziana, Mazzaschi, Giulia, Vivo, Valentina, Barocelli, Elisabetta, Tiseo, Marcello, Petronini, Pier Giorgio, Ardizzoni, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696146/
https://www.ncbi.nlm.nih.gov/pubmed/29190880
http://dx.doi.org/10.18632/oncotarget.19279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696146/
https://www.ncbi.nlm.nih.gov/pubmed/29190880
http://dx.doi.org/10.18632/oncotarget.19279

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