The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells

The catabolism of tryptophan (Trp) by indoleamine 2,3-dioxygenase (IDO) is a key step in tolerance effected by a variety of cell types, including mesenchymal stromal cells (MSCs). Trp catabolism generates molecules known as kynurenines, whose tolerance mechanisms involve activation of the Aryl Hydro...

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Detalles Bibliográficos
Autores principales: Lewis, Holly C., Chinnadurai, Raghavan, Bosinger, Steven E., Galipeau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696151/
https://www.ncbi.nlm.nih.gov/pubmed/29190885
http://dx.doi.org/10.18632/oncotarget.20166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696151/
https://www.ncbi.nlm.nih.gov/pubmed/29190885
http://dx.doi.org/10.18632/oncotarget.20166

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