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PTTG1 cooperated with GLI1 leads to epithelial-mesenchymal transition in esophageal squamous cell cancer

Pituitary tumor-transforming gene-1 (PTTG1) could acquire its metastasis-promoting effects via inducing epithelial-mesenchymal transition (EMT). However, its role and mechanism in EMT in esophageal squamous cell cancer (ESCC) had not been clearly elucidated. Here, we demonstrated that PTTG1 was over...

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Detalles Bibliográficos
Autores principales: Feng, Wang, Xiaoyan, Xuan, Shenglei, Li, Hongtao, Liu, Guozhong, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696190/
https://www.ncbi.nlm.nih.gov/pubmed/29190924
http://dx.doi.org/10.18632/oncotarget.21343