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Multi-omics analysis reveals that ornithine decarboxylase contributes to erlotinib resistance in pancreatic cancer cells

Molecular and metabolic alterations in cancer cells are one of the leading causes of acquired resistance to chemotherapeutics. In this study, we explored an experimental strategy to identify which of these alterations can induce erlotinib resistance in human pancreatic cancer. Using genetically matc...

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Detalles Bibliográficos
Autores principales: Jang, Won-Jun, Choi, Boyeon, Song, Sang-Hoon, Lee, Naeun, Kim, Dong-Joon, Lee, Sooyeun, Jeong, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696217/
https://www.ncbi.nlm.nih.gov/pubmed/29190951
http://dx.doi.org/10.18632/oncotarget.21572