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Cyclooxygenase-2 mediated synergistic effect of ursolic acid in combination with paclitaxel against human gastric carcinoma

Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). Paclitaxel (PTX) is an important chemotherapy agent used to treat solid tumors. We evaluated the in vitro antitumor activity of UA in combination with PTX against gastric cancer cells and investigated...

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Detalles Bibliográficos
Autores principales: Xu, Xian, Zhu, Guo-Qin, Zhang, Kai, Zhou, Yi-Chan, Li, Xiao-Lin, Xu, Wei, Zhang, Hao, Shao, Yun, Zhang, Zhen-Yu, Sun, Wei-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696220/
https://www.ncbi.nlm.nih.gov/pubmed/29190954
http://dx.doi.org/10.18632/oncotarget.21576