Cargando…

Cyclooxygenase-2 mediated synergistic effect of ursolic acid in combination with paclitaxel against human gastric carcinoma

Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). Paclitaxel (PTX) is an important chemotherapy agent used to treat solid tumors. We evaluated the in vitro antitumor activity of UA in combination with PTX against gastric cancer cells and investigated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xian, Zhu, Guo-Qin, Zhang, Kai, Zhou, Yi-Chan, Li, Xiao-Lin, Xu, Wei, Zhang, Hao, Shao, Yun, Zhang, Zhen-Yu, Sun, Wei-Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696220/ https://www.ncbi.nlm.nih.gov/pubmed/29190954 http://dx.doi.org/10.18632/oncotarget.21576

Ejemplares similares

Synergistic effect of xylitol and ursolic acid combination on oral biofilms
por: Zou, Yunyun, et al.
Publicado: (2014)

Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer
por: Shan, Jianzhen, et al.
Publicado: (2016)

Synergistic immunotoxin-paclitaxel combination against lymphoma
por: Müller, Fabian
Publicado: (2017)

Combined Effects of Cyclooxygenase-1 and Cyclooxygenase-2 Selective Inhibitors on Ovarian Carcinoma in Vivo
por: Li, Wei, et al.
Publicado: (2011)

The Synergistic Reducing Drug Resistance Effect of Cisplatin and Ursolic Acid on Osteosarcoma through a Multistep Mechanism Involving Ferritinophagy
por: Tang, Zhen, et al.
Publicado: (2021)

Synergistic combination therapy of lung cancer using paclitaxel- and triptolide-coloaded lipid–polymer hybrid nanoparticles
por: Liu, Jia, et al.
Publicado: (2018)

Combination of Oncolytic Measles Virus and Ursolic Acid Synergistically Induces Oncolysis of Hepatocellular Carcinoma Cells
por: Liu, Ching-Hsuan, et al.
Publicado: (2023)

Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts
por: LI, WEI, et al.
Publicado: (2013)

A phase Ib/II study of fruquintinib in combination with paclitaxel as the second‐line therapy for advanced gastric cancer
por: Zhang, Yang, et al.
Publicado: (2022)

In vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma
por: Yu, YanXin, et al.
Publicado: (2017)

Asparagus officinalis combined with paclitaxel exhibited synergistic anti-tumor activity in paclitaxel-sensitive and -resistant ovarian cancer cells
por: Zhang, Xin, et al.
Publicado: (2022)

Synergistic effect of ursolic acid and piperine in CCl(4) induced hepatotoxicity
por: Biswas, Sayan, et al.
Publicado: (2021)

Combining Paclitaxel with ABT-263 Has a Synergistic Effect on Paclitaxel Resistant Prostate Cancer Cells
por: Wang, Chihuei, et al.
Publicado: (2015)

Efficacy and safety of the combination of paclitaxel and platinum in advanced thymic carcinoma
por: Xu, Jian‐ping, et al.
Publicado: (2015)

The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin
por: Soica, Codruţa, et al.
Publicado: (2014)

Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88
por: Xiang, Fenfen, et al.
Publicado: (2019)

Interaction of Cyclooxygenase-2 with Helicobacter pylori Induces Gastric Chronic Nonresolving Inflammation and the Formation of Syndrome of Internal Block of Static Blood in Helicobacter pylori-Related Gastric Diseases
por: Dai, Yun-kai, et al.
Publicado: (2020)

Ethoxycarbonylmethyl ursolate
por: Yang, Wei, et al.
Publicado: (2008)

Ursolic acid derivatives are potent inhibitors against porcine reproductive and respiratory syndrome virus
por: Chen, Yang, et al.
Publicado: (2020)

Effects of Cyclooxygenase Inhibitors in Combination with Taxol on Expression of Cyclin D1 and Ki-67 in a Xenograft Model of Ovarian Carcinoma
por: Li, Wei, et al.
Publicado: (2012)

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells
por: Kyakulaga, Al Hassan, et al.
Publicado: (2020)

Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines
por: Refolo, Maria Grazia, et al.
Publicado: (2020)

Efficacy and safety of liposome-paclitaxel/liposome-paclitaxel combined with S-1 in 17 advanced gastric cancer patients with poor performance status
por: Wu, Runhong, et al.
Publicado: (2019)

Ursolic acid: biological functions and application in animal husbandry
por: Liu, Guanhui, et al.
Publicado: (2023)

Ursolic acid in health and disease
por: Seo, Dae Yun, et al.
Publicado: (2018)

Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility
por: Ji, Xuan-Ke, et al.
Publicado: (2021)

Ursolic acid silences CYP19A1/aromatase to suppress gastric cancer growth
por: Ma, Wen‐Lung, et al.
Publicado: (2022)

[Retracted] Ursolic acid suppresses the biological function of osteosarcoma cells
por: Pei, Yi, et al.
Publicado: (2023)

Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo
por: Xu, Chang-Geng, et al.
Publicado: (2019)

Synergistic Effects of Apigenin and Paclitaxel on Apoptosis of Cancer Cells
por: Xu, Yimiao, et al.
Publicado: (2011)

The Synergistic Antitumor Activity of Chidamide in Combination with Bortezomib on Gastric Cancer
por: Zhang, Wanjun, et al.
Publicado: (2020)

Ursolic Acid Inhibits the Proliferation of Gastric Cancer Cells by Targeting miR-133a
por: Xiang, Fenfen, et al.
Publicado: (2015)

Cyclooxygenase-2 in Endometriosis
por: Lai, Zhen-Zhen, et al.
Publicado: (2019)

Reactive Oxygen Species-Responsive Nanococktail With Self-Amplificated Drug Release for Efficient Co-Delivery of Paclitaxel/Cucurbitacin B and Synergistic Treatment of Gastric Cancer
por: Pang, Lijun, et al.
Publicado: (2022)

Synergistic antitumor effect of puerarin combined with 5-fluorouracil on gastric carcinoma
por: GUO, XU-FENG, et al.
Publicado: (2015)

Ursolic Acid Derivatives as Potential Agents Against Acanthamoeba Spp.
por: Sifaoui, Ines, et al.
Publicado: (2019)

Evidence of the Beneficial Effects of Ursolic Acid against Lung Cancer
por: Kornel, Amanda, et al.
Publicado: (2022)

Combination treatment with cisplatin, paclitaxel and olaparib has synergistic and dose reduction potential in ovarian cancer cells
por: Gao, Jianwen, et al.
Publicado: (2021)

Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model
por: Yin, Jianhai, et al.
Publicado: (2018)

Microwave-Assisted Extraction of Oleanolic Acid and Ursolic Acid from Ligustrum lucidum Ait
por: Xia, En-Qin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_v6h947o26trasthmnsdpu5hu5f