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Differential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method

Triple negative breast cancer (TNBC) is a group of cancers whose heterogeneity and shortage of effective drug therapies has prompted efforts to divide these cancers into molecular subtypes. Our computational platform, entitled GenEx-TNBC, applies concepts in systems biology and polypharmacology to p...

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Detalles Bibliográficos
Autores principales: Wathieu, Henri, Issa, Naiem T., Fernandez, Aileen I., Mohandoss, Manisha, Tiek, Deanna M., Franke, Jennifer L., Byers, Stephen W., Riggins, Rebecca B., Dakshanamurthy, Sivanesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696233/
https://www.ncbi.nlm.nih.gov/pubmed/29190967
http://dx.doi.org/10.18632/oncotarget.21669